Pathology EMQ template

 

YourName: Susan Jawad

YourIdentifier: 00356263

Theme: HIV Infection

 

OPTION LIST

 

A

IBS

I

2 NNRTIs+ 1 NRTIs

B

IRS

J

2 NRTIs + 1 PI

C

PPI

K

1 PI + 2 NRTIs

D

HAART

L

 

E

Penicillin

M

 

F

Ganciclovir

N

 

G

Zidovudine

O

 

H

Aciclovir

P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. This nucleoside analogue reverse transcriptase inhibitor (NRTI) is taken up by infected CD4+ cells and phosphorylated by intracellular kinases to a triphosphate.

 

 

2. The mechanism of action of this drug is it acts as a DNA chain terminator in CD4+ cells infected with HIV.

 

 

3. The commencement of this therapy is indicated when the CD4+ count falls below 350/mm3.

 

 

4. HAART is comprised of at least three drug groups. This is the most likely combinations of these drugs.

 

 

5. A condition reported around 12 weeks after starting HAART which usually resolves when immune function improves.

 

 

ANSWERS

1. G

2. G

3. D

4. J

5. B